Precision Cosmetic Laser and Surgery

Photodynamic Therapy with A.L.A for Non-Melanotic Skin Cancers

 
There are 4 Basic Types of Skin Cancer
 

(1) BCC (Basal Cell Carcinoma)
This is the most common type of skin cancer. It may be skin coloured, red or pale and it may be raised, flat or ulcerated. It typically occurs on areas of the body exposed to sun. It is usually slow growing, but sometimes can spread locally more rapidly.

(2) Bowens Disease (Intraepidermal Squamous Cell Carcinoma)
This is also common and is usually flat, red and scaly. It is slow growing but can become quite large if left untreated. Occasionally it can turn into a squamous cell carcinoma. It typically occurs on sun exposed areas of the body.

(3) Squamous Cell Carcinomas
This is less common than BCC and Bowens but still frequently seen in a skin cancer practice. It is typically raised and nodular. It is more aggressive than BCC and Bowens and can spread to local lymph glands.

(4) Melanoma
This is usually brown or black and somewhat irregular. An important clue is if it has changed over the previous few months. It is deadly and if discovered too late, can spread to lymph glands and other organs.
 

What can be Treated with Photodynamic Therapy (PDT)?
 

BCC and Bowens Disease are successfully treated with PDT. PDT is unproven in the treatment of SCC and it cannot be used for melanoma.

PDT can also be used for Solar Keratoses. Solar Keratoses are commonly known as “sunspots” and they are usually red, flat and scaly although sometimes they can be raised. They are areas of damage in the skin but are not a skin cancer (Although a small number can later turn into skin cancers).
     

What is PDT?
  PDT works by emitting a red light of a wavelength (630mm) that specifically targets a chemical (A.L.A) that has been earlier applied to the skin cancer. A photochemical reaction then occurs which selectively destroys the skin cancer cells.
 
How Does PDT Work?
 

PDT works by emitting a red light of a wavelength (630mm) that specifically targets a chemical which has been earlier applied to the skin cancer. A photochemical reaction then occurs which selectively destroys the skin cancer cells.
 

How Effective is PDT?
  The effectiveness of PDT has been proven in international clinical studies since 1996. A study with Solar Keratoses (with a 1 year follow-up) demonstrated 100% clearance rate. 2 studies with Bowens Disease (follow-up from 1 to 5 years) demonstrated a 90 to 100% clearance rate. 6 studies with BCC (follow-up 1 to 6 years) demonstrated a 86 to 100% clearance rate.
 
What are the Advantages of PDT?
  PDT is able to selectively destroy skin cancer cells with minimal damage to surrounding tissue. Cosmetic outcome is excellent with visible scarring being absent or minimal.
Cryotherapy, curettage, electrocautery, irradiation and surgery, however, are not able to spare normal tissue and will always result in scarring or loss of skin pigment.
 
What is a PDT Treatment Like?
  At the beginning of the day, you need to attend the practice where a special photosensitising cream (ALA) is applied to the lesion. A simple dressing will then be applied to cover the site. After 4 to 6 hours the dressing will be removed and the skin will be illuminated with pure red light. When the treatment has finished, a special dressing will be applied which will exclude light. This must be left on for 36 hours.
 
Is the Treatment Painful?
  Some patients may require a local anaesthetic injection whereas others may not, depending on the site of the lesion.
 
What Happens After the Treatment?
  When the dressing is removed after 36 hours, a crust may form which will come away by itself after several days.
 
How Many Treatments are Necessary?
  Usually only 1 treatment is necessary but occasionally a second is required for some thicker lesions.
 
Results of PDT for Skin Cancers:
 
Skin Cancer
Skin Cancer
Before
After
 
Skin Cancer
Skin Cancer
Before
After
   
Skin Cancer
Skin Cancer
Before
After
 
What is the Cost?
  The consultation with the doctor is $60.00, from which you can claim back $25.00 from Medicare. The cost of the PDT is usually $220.00 although larger lesions and lesions on the face may cost more. If more than 1 lesion is being treated, the other lesions will be charged at half price.
 

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